Ketamine Treatment for Treatment-Resistant Depression

Ketamine Treatment for Treatment-Resistant Depression 1

What is Treatment-Resistant Depression?

Depression is a widespread health issue and a leading cause of disability worldwide. According to the World Health Organization, over 264 million people globally suffer from depression. If conventional treatments such as talk therapy, medication, and lifestyle changes fail to deliver results for a specific patient with depression, the case is known as treatment-resistant depression (TRD).

Ketamine Treatment for Treatment-Resistant Depression 2

Why Ketamine?

Ketamine is a medication primarily used for anesthesia, pain relief, and sedation. However, it was found to have rapid and robust antidepressant effects when given at a subanesthetic dose. The clinical trials of ketamine started in the early 2000s, and it was found to treat TRD effectively. Ketamine treatment involves a highly-controlled administration of the medication in a safe environment by a licensed healthcare practitioner. Wish to learn more about the topic discussed in this article? Ketamine Treatments Austin, packed with extra and worthwhile details to enhance your study.

How Does Ketamine Work?

Ketamine works on the brain’s neurotransmitter systems, including glutamate and serotonin. According to some studies, it is believed that ketamine works by increasing neuroplasticity, which helps to create new neural pathways and repair damage in the brain cells caused by chronic stress and depression. Ketamine is unique from other anti-depressants, which typically take weeks and sometimes months to work; ketamine treatment can deliver results just hours after infusion.

What Can Patients Expect During Ketamine Treatment?

Before starting the treatment, patients need to undergo a medical evaluation and provide their health history to a licensed healthcare practitioner. During the treatment, patients receive an intravenous infusion of ketamine. Each session takes around 45 minutes to an hour, and patients need to be supervised by a healthcare professional for several hours after the infusion to ensure that they are stable and safe to leave.

Is Ketamine Treatment Safe?

Ketamine has been used for over five decades for anesthesia. The safety of ketamine at subanesthetic doses has been extensively studied in clinical trials for TRD. Ketamine treatment is generally considered safe and well-tolerated. Some patients may experience side effects such as dissociation, dizziness, and nausea during or shortly after treatment. However, these side effects are usually mild and temporary.

Is Ketamine Treatment Effective?

According to clinical studies, ketamine treatment’s effectiveness for TRD ranges from 60% to 70%. The results of ketamine treatment can last from several days to weeks, and in some cases, the antidepressant effects can last for several months. While ketamine treatment does not work for everyone, it has been found to be effective for many patients with TRD and can offer a new hope for individuals who have struggled with depression for years.


In conclusion, ketamine treatment offers a new option for patients suffering from TRD. The treatment is safe, well-tolerated, and has a high success rate. Ketamine’s rapid and robust antidepressant effects distinguish it from typical anti-depressants, which can take weeks and months to work. While ketamine treatment may not work for everyone, it is worth considering for individuals who have struggled with depression and have not found relief from conventional treatments. Dive deeper into the topic and reveal additional insights in this specially selected external resource. Ketamine Therapy Austin, explore new details and perspectives about the subject covered in the article.

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